KRIADEX ORAL SOLUTION CLONAZEPAM 2.50GR/1ML 20ML

In stock
$64.20 USD
ACTIVE INGREDIENT: CLONAZEPAM 2.50GR/1ML
CONTAINT: ORAL SOLUTION CLONAZEPAM 2.50GR/1ML 20ML
LABORATORY: PSICOFARMA
BRAND NAME: KRIADEX
Short description

Panic disorder KRIADEX is indicated for the treatment of panic disorder, with or without agoraphobia. Epilepsy. KRIADEX is indicated mainly as an adjuvant or in cases resistant to treatment, in most forms of epilepsy, especially absence seizures including atypical absence seizures; Lennox-Gastaut syndrome; myoclonic and atonic seizures. For infantile spasms (including West syndrome) and tonic-clonic seizures it is only indicated as an adjunct or in cases resistant to treatment.

Clonazepam exhibits pharmacological properties that are common to benzodiazepines, including anticonvulsant, sedative, muscle relaxant, and anxiolytic effects.
 
The central actions of benzodiazepines are mediated through enhancement of GABAergic neurotransmission at inhibitory synapses. In the presence of benzodiazepines, the affinity of the GABA receptor for the neurotransmitter is enhanced through positive allosteric modulation that results in increased action of released GABA on postsynaptic transmembrane chloride ion flux.
 
There are also some animal studies that show an effect on serotonin. Data from animal models and some electroencephalographic studies in man have shown that clonazepam rapidly suppresses many types of paroxysmal activity including spike-and-wave discharge in absence seizures (petit mal), slow spike waves, generalized spike waves. , spikes with temporal or other locations, as well as waves and irregular spikes.
 
Generalized EEG abnormalities are suppressed more regularly than focal abnormalities. According to this, clonazepam has beneficial effects in generalized and focal epilepsies.
 
Clonazepam is rapidly and almost completely absorbed after oral administration of Rivotril®. Peak plasma concentrations of clonazepam are reached within 1-4 hours. The absorption half-life is about 25 minutes. Absolute bioavailability is around 90% with large differences between individuals. Rivotril® tablets are bioequivalent to an oral solution with respect to the extent of absorption of clonazepam, while the rate of absorption is slightly less from tablets.
 
Steady-state plasma concentrations of clonazepam are 3-fold higher with a once-daily dosing regimen than after a single oral dose; the predicted accumulation rate for the 2 and 3 times daily regimens are 5 and 7, respectively. Following multiple oral doses of 2 mg 3 times daily, stable pre-dose plasma concentrations of clonazepam averaged 55 ng/mL. The plasma concentration-dose relationship of clonazepam is linear. The desired plasma concentration of clonazepam as an anticonvulsant varies from 20 to 70 ng/ml. Severe toxic effects including increased seizure frequency developed in most patients with steady-state plasma concentrations greater than 100 ng/mL. In patients with panic disorders; effective concentrations of clonazepam to reduce the frequency of panic attacks were about 20 ng/mL.
 
Clonazepam is rapidly distributed in various organs and tissues of the body with preferential reuptake by brain structures.
ACTIVE INGREDIENT
CLONAZEPAM 2.50GR/1ML
CONTAINT
ORAL SOLUTION CLONAZEPAM 2.50GR/1ML 20ML
LABORATORY
PSICOFARMA
BRAND NAME
KRIADEX
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What are your shipping rates and policies?
At the moment we offer 1 shipping option:

Regular Airmail Delivery (10-12 business days)
 
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.

Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).

You can view our shipping rate and other information after selecting a particular product.

Do you ship internationally?
yes
 
In what currency is my purchase transaction received?
The currency used will be the US dollar.

How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.

Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico

Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.

What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years

What is your return policy?
Read the refund and cancellation policy

We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
 
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.

What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.

How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.

What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.

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