PRISTIQ ER DESVENLAFAXINE SUCCINATE 100MG 28TABS

In stock
$202.06 USD
ACTIVE INGREDIENT: DESVENLAFAXINE SUCCINATE 100MG
CONTAINT: 28 TABLETS
LABORATORY: PFIZER
BRAND NAME: PRISTIQ ER
Short description

It is indicated for: • Treatment of major depressive disorder (MDD) in men and women. • Acute and maintenance treatment of MDD. • Moderate to severe vasomotor symptoms (SVM) associated with menopause.

Non-clinical studies have shown desvenlafaxine succinate to be a selective serotonin and norepinephrine reuptake inhibitor (SNRI). The efficacy of desvenlafaxine succinate is believed to be related to the potentiation of the neurotransmitters serotonin and norepinephrine in the central nervous system.
 
In vitro, desvenlafaxine lacks significant affinity for numerous receptors, including muscarinic-cholinergic, H1-histaminergic, or α1-adrenergic receptors. The same binding profile assay shows that desvenlafaxine also lacks significant affinity for several ion channels, including calcium, chloride, potassium, and sodium channels, as well as monoamine oxidase (MAO) inhibitory activity.
 
Studies in major depressive disorder: The efficacy of desvenlafaxine for the treatment of MDD was studied in patients who met the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) diagnostic criteria for major depressive disorder. Overall, doses of 50-400 mg/day showed efficacy in four short-term (8-week), randomized, double-blind, placebo-controlled studies and two relapse prevention trials conducted in adult outpatients with major depressive disorder. Desvenlafaxine demonstrated superiority over placebo as measured by improvement in the 17-item Hamilton Depression Rating Scale (HAM-D) total score and the Clinical Global Impression of Improvement Scale ( Clinical Global Impressions Scale – Improvement, CGI-I). Pooled analysis of these studies showed a mean difference from placebo in change from baseline in HAM-D17 scale score of 1.5 (0.9, 2.1), 2.2 (1.4, 2.9), and 2.4 (1.2, 3.6). for the 50 mg/day, 100 mg/day, and 200 mg/day doses, respectively.
 
The percentage of patients with CGI-I scores of 1 (very much improved) or 2 (very much improved) ranged from 55 to 61% for desvenlafaxine (dose 50 to 200 mg/day) compared to 45% in the placebo group.
 
Of the 7,785 patients evaluated in premarketing clinical studies with desvenlafaxine, 5% were 65 years of age or older. No overall differences in efficacy were observed between these patients and younger patients.
ACTIVE INGREDIENT
DESVENLAFAXINE SUCCINATE 100MG
CONTAINT
28 TABLETS
LABORATORY
PFIZER
BRAND NAME
PRISTIQ ER
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What are your shipping rates and policies?
At the moment we offer 1 shipping option:

Regular Airmail Delivery (10-12 business days)
 
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.

Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).

You can view our shipping rate and other information after selecting a particular product.

Do you ship internationally?
yes
 
In what currency is my purchase transaction received?
The currency used will be the US dollar.

How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.

Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico

Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.

What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years

What is your return policy?
Read the refund and cancellation policy

We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
 
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.

What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.

How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.

What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.

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