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Short description

Tramadol is a centrally acting opioid pain reliever. It is a pure non-selective agonist at μ, δ and κ opioid receptors with a higher affinity for the μ receptor, thereby altering the perception of pain and the emotional response to it. Mu receptors are widely distributed throughout the CNS, especially in the limbic system, thalamus, striatum, hypothalamus, and midbrain, as well as in laminae I, II, IV, and V of the dorsal horn in the spinal cord. Kappa receptors are located mainly in the medulla and the cerebral cortex. Other mechanisms that contribute to its analgesic effect are inhibition of neuronal reuptake of norepinephrine and serotonin. Tramadol has an antitussive effect. Gastrointestinal motility is not affected. The effects of tramadol on the major and minor circulation and on the heart are scarce and clinically irrelevant, therefore there is no limitation for its use in coronary heart disease accompanied by pain. At therapeutic doses it does not cause alterations in the respiratory system. The potency of tramadol is reported to be 1/10 to 1/6 that of morphine.

Tramadol is a widely used synthetic opioid analgesic (painkiller) used to treat moderate to severe pain. Citra Tramadol is one specific brand offering this medication in a 50mg tablet form. This article provides a comprehensive overview of Citra Tramadol 50mg, including its uses, dosage, side effects, and important safety information.

What is Citra Tramadol 50 mg?

Tramadol 50 mg is a prescription medication used primarily to manage moderate to severe pain. Manufactured under the Citra brand, each tablet contains 50mg of Tramadol. This medication falls under the class of drugs known as opioid analgesics, which work by altering the brain's perception and response to pain.

Tramadol 50 is commonly prescribed for various types of pain, including post-surgical pain, chronic pain conditions like arthritis, or pain resulting from injury. It is an effective medication that can greatly improve the quality of life for individuals dealing with pain.

Citra Tramadol 50mg is an oral medication, typically available as round or oval tablets or capsules. The pill of Citra Tramadol is usually white or pink in color and may have a score line to facilitate dose adjustments if necessary.

How Does Tramadol 50 mg Work?

Tramadol operates on a dual mechanism of action. Firstly, it binds to the mu-opioid receptors in the brain, thereby reducing the pain signals sent to the brain. Secondly, it inhibits the reuptake of two neurotransmitters, serotonin and norepinephrine, amplifying their effects and contributing to pain relief.

Mechanism of action

Tramadol Citra 50, like other forms of tramadol, operates through a dual mechanism of action to alleviate pain.

  • Opioid Receptor Agonism: Tramadol is an agonist of the mu-opioid receptors, which are involved in the perception of pain and the body's pain response. By binding to these receptors, tramadol mimics the action of endogenous opioids (like endorphins), reducing the perception of pain in the body.

  • Reuptake Inhibition: Tramadol also acts as a reuptake inhibitor for the neurotransmitters serotonin and norepinephrine. This means it prevents these neurotransmitters from being absorbed back into the nerve cells in the brain and spinal cord after they have been released. This inhibition results in an increase of these neurotransmitters in the synaptic cleft (space between neurons), which helps to modulate and decrease the pain signals, thus enhancing pain relief.

These two actions together give tramadol its unique pain-relieving properties. It's important to note, however, that the body can develop a tolerance to tramadol over time, and the drug should only be taken under the supervision of a healthcare provider due to its potential for dependence and addiction.

Dosage and Administration

Tramadol 50mg tablet is generally taken orally with or without food. However, if you have nausea, taking the medication with food may help reduce this symptom.
As for the dosage, it greatly depends on the patient's medical condition and response to treatment. The usual recommended dose for adults is 50-100mg every four to six hours as needed for pain. The maximum recommended daily dose is 400mg. For some patients, starting at a lower dose (25mg/day) and gradually increasing the dosage may help reduce side effects.

Remember to take Tramadol pills 50mg exactly as prescribed by your healthcare provider. It's important to follow the instructions carefully to avoid risks such as addiction or overdose. It's also crucial not to suddenly stop taking this medication without discussing it with your doctor, as this can lead to withdrawal symptoms.
In the case of elderly patients, or patients with liver or kidney issues, the dosage might be adjusted by your healthcare provider due to slower metabolism and excretion of the drug.
For the best effects, this medication should be taken regularly. If it's taken for a prolonged period, it may not work as effectively and may require a different medication strategy.

Potential Side Effects

As with any medication, Tramadol 50 can cause side effects. The most common ones include nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, or sweating. These side effects may decrease as your body gets used to the medication. If these side effects persist or worsen, seek medical attention immediately.

Serious side effects are less common but may include mental/mood changes (such as agitation, hallucinations), severe stomach/abdominal pain, difficulty urinating, signs of your adrenal glands not working well (such as loss of appetite, unusual tiredness, weight loss). In case of any serious side effects, you should contact your doctor promptly.

Precautions and Warnings

Certain conditions may contraindicate the use 50 mg of Tramadol, such as severe asthma or breathing problems, a blockage in the stomach or intestines, if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications, or if you have used an MAO Inhibitor in the past 14 days.

Tramadol Citra may be habit-forming, and misuse can lead to addiction, overdose, or death, especially in a person using the drug without a prescription. Therefore, it's critical to take this medication exactly as prescribed by your healthcare provider.


Certain medications may interact with Tramadol Citra 50, including other opioid pain medications, mental health drugs (like antidepressants or antipsychotics), certain antibiotics, and heart medications. Always inform your healthcare provider about all the medications you are currently taking to avoid harmful interactions.

Citra Tramadol 50mg and Special Populations

The use of Tramadol pills 50 mg should be closely monitored in children, the elderly, pregnant women, and breastfeeding mothers. For elderly patients, the dosage may need to be adjusted as their liver and kidney function may not be as efficient, causing the drug to be processed more slowly.
Pregnant women should avoid using Tramadol 50 mg pill as it could potentially harm the unborn baby. In addition, traces of Tramadol can pass into breast milk and may cause side effects in a nursing infant. Therefore, breastfeeding mothers should discuss the potential risks and benefits with their healthcare provider before taking this medication.
In patients with liver or kidney disease, a lower dose or extended dosing interval may be required as these conditions may affect how the active substance is metabolized and eliminated from the body.

What to Do in Case of Overdose

Overdosing Tramadol 50 mg can be life-threatening. Symptoms of overdose can include slow breathing, slow heartbeat, severe drowsiness, fainting, and coma.

Proper Storage and Disposal

Citra Tramadol should be stored at room temperature, away from light and moisture. Do not store it in the bathroom. Unused or expired medications should be disposed of properly to prevent accidental consumption.

Frequently Asked Questions

Q: Can I drink alcohol while taking Citra Tramadol 50mg?

A: No, combining alcohol with Tramadol can lead to dangerous side effects or death.

Q: Can I drive or operate heavy machinery while taking this medication?

A: Tramadol can impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.

Q: Can I stop taking Tramadol abruptly?

A: No, stopping Tramadol suddenly can lead to withdrawal symptoms. Always consult with your healthcare provider for a safe discontinuation plan.

Q: How strong is 50 mg of Tramadol?

A: Tramadol is a potent prescription painkiller. A 50mg dose of Tramadol is a relatively moderate dose, but its strength and effectiveness can vary significantly depending on the individual taking it. Factors like body weight, overall health, the type and intensity of pain being treated, and individual sensitivity to the medication can all influence how "strong" a 50mg dose of Tramadol may feel.

It's also worth noting that Tramadol has a dual mechanism of action. It works both as an opioid pain reliever and as a medication that affects serotonin and norepinephrine, neurotransmitters in your brain. This unique mechanism contributes to its pain-relieving capabilities.

That said, it's crucial to take Tramadol only as directed by a healthcare professional. Even though 50mg is not a high dose, misuse of Tramadol can still lead to serious side effects, including dependency and overdose. If you feel that your current dose is not effectively managing your pain, you should consult with your doctor rather than increasing the dose on your own.

Q: How to take tramadol 50 mg for nerve pain?

A: Tramadol 50mg is typically used for moderate to moderately severe pain, including nerve pain. The way you take it can depend on the specific product you are prescribed, your individual medical condition, and your body's response to treatment.

Here are general instructions for taking Tramadol:

When and How Often to Take It: Tramadol is usually taken every 4 to 6 hours as needed for pain relief. You should not take more than the maximum recommended dose (usually 400 mg per day for adults) in any 24-hour period.

Taking it With or Without Food: Tramadol can be taken with or without food. However, if the medication makes you feel nauseous, taking it with food may help reduce this symptom.

Swallowing the Tablet: Swallow the tablet whole with a drink of water. Do not crush, break, or chew it. This is particularly important for extended-release forms of the medication, which are designed to release the drug slowly over time.

Follow Your Doctor's Instructions: Always follow your doctor's instructions about when and how to take your medication. Your doctor will determine the most appropriate dosage for your specific needs, based on factors like your pain level, other medications you're taking, and your overall health status.

It's important to note that while Tramadol can help manage nerve pain, it does not cure the underlying cause of the pain. Therefore, it should be used as part of a comprehensive treatment plan that may include other medications, physical therapy, or other treatments as advised by your healthcare provider.

As with any medication, Tramadol can have side effects and has the potential for dependence and abuse.

It's essential not to suddenly discontinue Tramadol without consulting with your healthcare provider, as this could lead to withdrawal symptoms. Your doctor can provide guidance on how to safely stop using this medication if it's necessary.

Citra Tramadol 50mg is a powerful medication for managing moderate to severe pain. While it can significantly improve the quality of life for those struggling with pain, it must be used responsibly due to its potential for addiction and dependence. Always follow your healthcare provider's instructions regarding dosage and duration of treatment, and report any side effects promptly.

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